Immunity against Influenza Type A among 4-14-Years-Old Children in Kerman, Iran

Abstract: Background & Aims: Influenza viruses are important causes of mortality and morbidity in children. The aim of this study was to assess the presence of antibodies (IgG) against Influenza A in children in Kerman, Iran. Methods: In a cross-sectional study, 200 children aged 4-14 years referred to Besaat Clinic and Afzalipour hospital for diseases other than influenza were enrolled. Sera were tested for anti influenza A IgG with NovaLisa ELISA kits (NOVATEC, Germany). Results: Anti-Influenza virus A IgG was detected in 12% (24/200) of the sera. This group had the highest mean age [9.62 (7-12) years]. Among studied variables, only age was related to seropositivness for anti-Influenza A serotypes. Conclusion: The majority of children aged 4-14 years in Kerman had no immunity to Influenza A. So, they are at risk for influenza and its morbidity during possible epidemics of this infection. Keywords: Influenza A, Immunity, Childre

Immunity against Influenza Type A among 4-14-Years-Old Children in Kerman, Iran

Abstract: Background & Aims: Influenza viruses are important causes of mortality and morbidity in children. The aim of this study was to assess the presence of antibodies (IgG) against Influenza A in children in Kerman, Iran. Methods: In a cross-sectional study, 200 children aged 4-14 years referred to Besaat Clinic and Afzalipour hospital for diseases other than influenza were enrolled. Sera were tested for anti influenza A IgG with NovaLisa ELISA kits (NOVATEC, Germany). Results: Anti-Influenza virus A IgG was detected in 12% (24/200) of the sera. This group had the highest mean age [9.62 (7-12) years]. Among studied variables, only age was related to seropositivness for anti-Influenza A serotypes. Conclusion: The majority of children aged 4-14 years in Kerman had no immunity to Influenza A. So, they are at risk for influenza and its morbidity during possible epidemics of this infection. Keywords: Influenza A, Immunity, Childre